Round 10: Tossup 15

Cholera toxin ADP ribosylates a protein’s G-s-alpha subunit, thereby preventing this reaction from occurring. (-5[1])The mechanism of most glycosidases occurs through this type of reaction. Performing this reaction on amides results in carboxylic acids. In muscle contraction, this type (-5[1])of reaction re-positions the myosin head, readying (15[1])it to bind to (*) actin. Once a protein is tagged by ubiquitin, it is subjected (-5[1])to this type of reaction. This reaction, which releases ADP and an inorganic phosphate (-5[1])when it is done on ATP, is the opposite of dehydration synthesis. For 10 points, name this reaction that uses water to break (10[1])down macromolecules. (10[2])■END■ (10[2])

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