Packet 5: Tossup 13

Binding of the Hrs protein to ubiquitin and Pl(3)P (“P-L-three-P”) stimulates this process by kickstarting the (-5[1])ESCRT (“escort”) complex. After AP2 binds (-5[1])to a tyrosine-laden motif on a cytoplasmic “tail,” it recruits a triskelion-shaped (-5[1])molecule that mediates (15[1])this process. This process can occur through caveolae, but its most common type is receptor-mediated, taking place through pits coated with (*) clathrin. The “late” product of this process undergoes fusion with the lysosome. (10[1])This process involves stabilization of membrane curvature and the formation (10[1])of vesicles. For 10 points, name this process in which (0[1])a (10[1])cell takes up molecules (10[1])in contrast (10[1])to (10[2])exocytosis. (10[1])■END■ (10[3])

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