Round 5: Tossup 13

Binding of the Hrs protein to ubiquitin and Pl(3)P stimulates this process by kickstarting the ESCRT (“escort”) complex. After AP2 binds to a tyrosine-laden (-5[1])motif on a cytoplasmic “tail,” it recruits a triskelion-shaped molecule that mediates this process. This process can occur through caveolae, but its most common type is receptor-mediated, taking place through pits coated with (*) clathrin. The “late” product of this process undergoes fusion with the lysosome. This process involves stabilization of membrane curvature and the formation of vesicles. For 10 points, name this process in which a cell takes up molecules in contrast to exocytosis. ■END■ (10[2])

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