Round 9: Tossup 16

The donation of this functional group is accomplished by a cofactor consisting of an s-adenosyl group attached to an amino acid. The enzyme Dam in E. coli donates this functional group, which marks the template strand during mismatch repair. Uracil and thymine solely differ by the presence of this functional group. CpG islands are hotspots for the (*) addition of this functional group near promoter (-5[1])sequences. Unlike the addition of an acetyl group, the addition of this functional group on histones can either (10[1])repress or active transcription. For 10 points, (10[1])name this one carbon functional group symbolized (-5[1])CH3. ■END■ (10[2])

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