Round 9: Tossup 16

The donation of this functional group is accomplished by a cofactor consisting of an s-adenosyl (15[1])group attached to an amino acid. The enzyme Dam in E. coli (-5[1])donates this functional group, which marks the template strand during mismatch repair. Uracil and thymine solely differ by the presence of this functional group. (-5[1])CpG islands are hotspots for the (*) addition of this functional group near promoter sequences. Unlike the addition of an acetyl group, (10[1])the addition of this functional (10[1])group on histones (10[1])can either repress or active transcription. For 10 points, name this one carbon functional group symbolized CH3. ■END■

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